A decade in the past, kratom advocates fought a surprisingly profitable marketing campaign in opposition to a proposed Drug Enforcement Administration ban that claimed the obscure Southeast Asian plant posed “an imminent hazard to public security.”
They gained bipartisan allies from Bernie Sanders to Rand Paul, and helped create a billion-dollar industry out of kratom, which has pain-relieving results they mentioned may assist struggle the opioid epidemic as a far safer, pure various to capsules.
Now, lots of those self same pro-kratom activists are calling for a ban on merchandise containing concentrates of certainly one of kratom’s lively elements: 7-hydroxymitragynine, or 7-OH, an ultra-potent extract with opioid-like results. And it’s inflicting main friction amongst shoppers, sellers, and advocates of each substances.
“It is a chemically manipulated, full-blown opioid that’s now within the market,” claims Mac Haddow, the senior public coverage fellow on the American Kratom Affiliation, a kratom business foyer group. “They masquerade as kratom merchandise.”
The proliferation of 7-OH in gummies, capsules, and pictures with model names like Magic 7OH, 7 O’Heaven, and Pure OHMS throughout hundreds of gasoline stations and nook shops over the previous few years has triggered rising consternation. Customers of 7-OH have spoken of its excruciating withdrawal signs, and there have been reports of polydrug overdoses involving 7-OH and different substances. Some at the moment are coming into rehab to beat their dependency, whereas others are self-detoxing based mostly on recommendation from Redditors.
The kratom neighborhood fears that 7-OH’s unhealthy fame may drag the complete kratom business right into a regulatory quagmire. However the 7-OH business has organized in opposition to the potential prohibition, claiming 7-OH is kratom, regardless of solely showing in hint quantities throughout the leaves of the kratom plant, and that its advantages as an analgesic outweigh its potential harms.
Anti-7-OH directives from the federal authorities have exacerbated tensions between the 2 sides.
Final July, US Well being and Human Companies secretary Robert F. Kennedy Jr. described the 7-OH business as “sinister” at a press convention the place FDA commissioner Marty Makary referred to as for the DEA to categorize the drug as Schedule I—probably the most restrictive class of banned substances. Talking from the Oval Workplace on Could 11, President Donald Trump publicly endorsed “pure 7-OH,” in complicated remarks which appeared to consult with kratom. On high of all that, it seems that each RFK Jr. and Division of Homeland Safety secretary Markwayne Mullin—who can also be pushing for a 7-OH crackdown—have robust ties to a kratom lobbyist (and convicted legal) behind a infamous kratom drinks firm.
Proponents of 7-OH see the substance and the plant it’s derived from as inexorably linked. In April 2025 testimony to Colorado legislators debating regulate kratom and 7-OH, Michele Ross, the chief scientific adviser to the 7-OH advocacy group 7-HOPE Alliance, wrote“To say 7-OH isn’t kratom is to say caffeine isn’t espresso or THC isn’t hashish. It merely doesn’t make sense.”
However versus espresso, hashish, and kratom—which have been consumed for hundreds of years if not hundreds of years—7-OH doesn’t have a protracted historical past of human use. It’s solely been available on the market for a couple of years.
Most of the merchandise which might be labeled 7-OH comprise little-understood compounds with unknown organic results in animals or people, says Chris McCurdy, a number one kratom researcher and director of the College of Florida’s translational drug growth core. “So, these merchandise, whereas represented as ‘clear’ are something however.”
In the meantime, a dozen states, from California to Vermont, according to studies, have already moved forward of federal scheduling with their very own 7-OH bans. Seven of these states have additionally banned kratom, though Rhode Island recently overturned its prohibition.
